Vacancies

Research Associate in the School of Cardiovascular and Metabolic Medicine & Sciences

Job ID: 049705
Grade and Salary : £38,826 – £39,882, including London Weighting Allowance
Contract Term:Full time
Contract Details:Prof Manuel Mayr, manuel.mayr@kcl.ac.uk / 020 7848 5446
Closing date: 31-Jul-2022

We are seeking a highly-motivated scientist to join our collaborative team of research and clinician scientists interested in cardiovascular disease. The post holder will be working towards the overall objectives of the cardiovascular proteomics research group headed by Prof. Mayr. We are looking for an experienced researcher with a biomedical background in cardiovascular science who will pursue collaborative international research with a project focus on harnessing proteomics data of clinical cohorts and providing expertise in molecular biology techniques. Prof. Mayr’s team has a strong clinical-translational focus and state-of-the-art proteomics equipment dedicated to cardiovascular research. The topic is not more predefined other than that the candidate needs to have the ability to conduct excellent science and keen to take advantage of biomedical mass spectrometry data for their research.

For examples, see the following PubMed IDs:
28319050 34099652 33340009 29030347 34806902 34601896 33149301

Key Responsibilities

Develop and undertake research of high quality consistent with making a full active research contribution in line with the Department/Division/School research strategy
Develop and undertake research projects related to cardiovascular diseases
Manage specific pieces of activity to an agreed timeline and within a specific budget including literature reviews, data collection and analysis, report writing
Attend and, as appropriate, present research findings and papers at internal academic meetings and external professional conferences, and to contribute to the internal and external visibility of the department
Work as a conscientious and committed member of the team in order to achieve the aims of the projects and the primary care group
Facilitate collaboration and networking which engages and supports the activities of the group
Participate in educational activities as appropriate to the stage of your career
Participate in the supervision and mentoring of students with projects related to the applicant’s expertise
To be committed to your own personal career development
Liaise with the administrative team for the support of the project
Contribute to publications arising from this project
Play a key role in the coordination of the design, testing and implementation of the range of qualitative and quantitative data collection instruments required in the evaluation of the study intervention
Undertake any other reasonable duties that may be relevant to the role outline

The above list of responsibilities may not be exhaustive, and the post holder will be required to undertake such tasks and responsibilities as may reasonably be expected within the scope and grading of the post.

Skills, Knowledge & Experience

Essential criteria

PhD awarded in Biological Sciences or PhD in Biological Sciences near completion
Molecular Biology skills
Knowledge in cardiovascular biology
Experience in studying cardiac and/or vascular cell types
Experience in cell culture of primary cells and cell lines
Experience in isolation of primary cardiac/vascular cells
Experience in fluorescence and confocal microscopy
Experience in basic biochemical/cellular/molecular techniques
Able to interact effectively within a research team and excellent interpersonal skills
Excellent verbal and written communication skills evidenced by oral/poster conference presentations and peer-reviewed publications
Excellent organisational skills and ability to work under pressure and prioritise competing demands on time

Desirable criteria

Experience with in vitro and in vivo models of cardiovascular disease
Basic experience in –omics analysis

To apply for this role, please register to download and submit the specified application form.

When applying, in the ‘Upload supporting documents’ section, please attach a personal statement to tell us why you are suitable for the role.

If you have questions about this role, please contact: Professor Manuel Mayr, Email: manuel.mayr@kcl.ac.uk

Research Associate (Maternity cover) in the School of Cardiovascular and Metabolic Medicine & Sciences

Job ID: 049691
Grade and Salary : £38,826 – £45,649, including London Weighting Allowance
Contract Term:Full time
Contract Details:Prof Manuel Mayr, manuel.mayr@kcl.ac.uk / 020 7848 5446
Closing date: 31-Jul-2022

We are seeking a highly motivated scientist to join our collaborative team of research and clinician scientists interested in cardiovascular disease. The post holder will be working towards the overall objectives of the cardiovascular proteomics research group headed by Prof. Mayr. We are looking for an experienced researcher with a biomedical background in cardiovascular science who will pursue collaborative international research with a project focus on harnessing proteomics data of clinical cohorts and providing expertise in molecular biology techniques. Prof. Mayr’s team has a strong clinical-translational focus and state-of-the-art proteomics equipment dedicated to cardiovascular research. The topic is not more predefined other than that the candidate needs to have the ability to conduct excellent science and keen to take advantage of biomedical mass spectrometry data for their research.

For examples, see the following PubMed IDs:
28319050 34099652 33340009 29030347 34806902 34601896 33149301

This post will be offered on a fixed-term contract for 12 months, with a possibility to extend after positive evaluation.
This is a full-time post.

Key Responsibilities

Develop and undertake research of high quality consistent with making a full active research contribution in line with the Department/Division/School research strategy
Develop and undertake research projects related to cardiovascular diseases
Manage specific pieces of activity to an agreed timeline and within a specific budget including literature reviews, data collection and analysis, report writing
Attend and, as appropriate, present research findings and papers at internal academic meetings and external professional conferences, and to contribute to the internal and external visibility of the department
Work as a conscientious and committed member of the team in order to achieve the aims of the projects and the primary care group
Facilitate collaboration and networking which engages and supports the activities of the group
Participate in educational activities as appropriate to the stage of your career
Participate in the supervision and mentoring of students with projects related to the applicant’s expertise
To be committed to your own personal career development
Liaise with the administrative team for the support of the project
Contribute to publications arising from this project
Play a key role in the coordination of the design, testing and implementation of the range of qualitative and quantitative data collection instruments required in the evaluation of the study intervention
Undertake any other reasonable duties that may be relevant to the role outline

Skills, Knowledge & Experience

Essential criteria

PhD awarded in Biological Sciences or PhD in Biological Sciences near completion
Molecular Biology skills
Knowledge in cardiovascular biology
Experience in studying cardiac and/or vascular cell types
Experience in cell culture of primary cells and cell lines
Experience in isolation of primary cardiac/vascular cells
Experience in fluorescence and confocal microscopy
Experience in basic biochemical/cellular/molecular techniques
Able to interact effectively within a research team and excellent interpersonal skills
Excellent verbal and written communication skills evidenced by oral/poster conference presentations and peer-reviewed publications
Excellent organisational skills and ability to work under pressure and prioritise competing demands on time

Desirable criteria

Experience with in vitro and in vivo models of cardiovascular disease
Basic experience in –omics analysis

To apply for this role, please register to download and submit the specified application form.

When applying, in the ‘Upload supporting documents’ section, please attach a personal statement to tell us why you are suitable for the role.

If you have questions about this role, please contact: Professor Manuel Mayr, Email: manuel.mayr@kcl.ac.uk

Senior Research Technician

Job ID: 049325
Grade and Salary : Salary: £37,804.00 per annum, including London Weighting Allowance (Grade 5.30)
Contract Term:Full time
Contact details: Prof Manuel Mayr, manuel.mayr@kcl.ac.uk
Closing date: 31-Jul-2022

The King’s College London British Heart Foundation (BHF) Centre of Research Excellence is designed to nurture interdisciplinary collaborations and bench-to-bedside projects in cardiovascular research. The School of Cardiovascular and Metabolic Medicine & Sciences is a core constituent of the BHF Centre where the cardiovascular proteomics group is led by Prof. Manuel Mayr. The cardiovascular proteomics research group ( www.vascular-proteomics.com) has the latest mass spectrometry equipment, established computational infrastructure and high experience in proteomics and multi-omics research projects.
The research work of the group encompasses a wide variety of wet and dry lab activities. These include molecular and cellular biology experimentation and support in specialist techniques. The post holder with work alongside the Schools Professional Services team, providing high quality technical support and assisting in laboratory research activities. It is expected that 50% of the time will be spent on ensuring the smooth running in the labs, including ensuring a high standard of cleanliness and sustainability within the lab, producing sterile preparations and provisions, servicing and maintaining equipment, management of chemical and stock supplies, and ensuring compliance with health and safety procedures as directed by the department. It is expected that 30% of the time will be dedicated to scientific services which support experimental research including aseptic tissue collection, tissue and cell culture and isolation of primary neonatal and adult cardiac myocytes from both mice and rats. The rest of the time will be spent providing experimental support for molecular and cellular biology experiments and participating in School projects and activities as directed.

This post will be offered on an a fixed-term contract for 2 years. This is a full-time post – 100% full time equivalent.

Key responsibilities

Provide in-depth knowledge of technical or scientific practices, methods and procedures gained through experience and/or formal education
Support a range of technical activities, providing research support and scientific services where there are established standards and requirements for service
Ensure the smooth day-to-day running of the labs, including equipment maintenance and resource management
Actively participate in Continuing Professional Development and training initiatives, in line with the Technician Commitment
Gain a strong understanding of the laboratory users’ requirements and appropriately align with changing priorities/needs

Skills, knowledge, and experience
The post requires a minimum level 4 qualification, plus work experience in a relevant technical/scientific post and knowledge and skills of a range of scientific practices and procedures applicable to the area of work. The successful applicant must demonstrate proven technical experience in a range of techniques in molecular biology, cell culture and histology, microscopy. The post holder must demonstrate an active commitment to professional development such as membership to a professional body, commitment to Continuing Professional Development and/or ongoing training or education activities.

Essential criteria

Minimum level 4 qualification e.g. higher apprenticeship, HNC or other Level 4 award
Previous work experience in a relevant technical/scientific post
Extensive knowledge and skills gained through work experience in a relevant technical or scientific post
Expertise in molecular biology, cell culture and/or histology
Working knowledge and understanding of Laboratory Health and Safety Regulations (COSHH, GMO (contained use), etc.) governing the area of work
Good computer skills, numeracy skills and ability to apply learnt techniques to the work context
Good planning and organization skills, with ability to manage own workload and work with minimal supervision
Excellent communication skills, orally and in writing, along with strong interpersonal and collaborative skills
Understanding of methodologies and techniques with a knowledge of a range of technical or scientific practices, methods of procedures applicable to the work area
Knowledge of environmental impacts of laboratory work and an interest in reducing the negative impacts
Strong commitment to Continuing Professional Development and active engagement in ongoing training and learning activities

Desirable criteria

Experience working in a biological services unit, with a strong understanding of the Animals (Scientific Procedures) Act
Knowledge of Schedule 1 techniques, mutant colony breeding systems, and genotyping of transgenic mouse colonies
Experience in laboratory equipment maintenance and management of stock levels of consumables, supplies and in-house preparations
Experience of supervising/advising junior team members, giving feedback on performance levels and training/coaching where necessary

Further Information
The applicant should be able and willing to provide additional support beyond core hours as required.

This post is subject to Disclosure and Barring Service and Occupational Health clearance.

Molecular Biology; Cellular Biology; Senior Research Technician

To apply for this role, please register to download and submit the specified application form.

If you have questions about this role, please contact: Professor Manuel Mayr, Email: manuel.mayr@kcl.ac.uk