Dr. Elisa Duregotti
Education
| 2006-2009 | Bachelor Degree in Molecular Biology Faculty of Mathematical, Physical and Natural Sciences, University of Padova, Padova, Italy |
| 2009-2011 | Master Degree in Medical Biology (110/110 cum laude) Faculty of Mathematical, Physical and Natural Sciences, University of Padova, Padova, Italy |
| 2012-2014 | PhD in Biosciences and Biotechnologies (Cell Biology curriculum) Prof. Cesare Montecucco Lab., Department of Biomediacal Sciences, University of Padova, Padova, Italy |
Present Appointment
| 2023- | Research Associate National Heart and Lung Institute Imperial College London London, UK |
Previous Appointment
| 2015-2017 | Post-doctoral position Prof. Cesare Montecucco, Department of Biomedical Sciences, University of Padova, Padova, Italy |
| 2017-2023 | Research Associate, Cardiovascular Division, King’s College London, UK |
Publications
| 1 | Duregotti E, Reumiller CM, Mayr U, Hasman M, Schmidt LE, Burnap SA, Theofilatos K, Barallobre-Barreiro J, Beran A, Grandoch M, Viviano A, Jahangiri M, Mayr M. Reduced secretion of neuronal growth regulator 1 contributes to impaired adipose-neuronal crosstalk in obesity. Nature communications. 2022 13(1) : 7269. [Full Text] [PubMed] [DOI] |
| 2 | Reed E, Fellows A, Lu R, Rienks M, Schmidt L, Yin X, Duregotti E, Brandt M, Krasemann S, Hartmann K, Barallobre-Barreiro J, Addison O, Cuello F, Hansen A, Mayr M. Extracellular Matrix Profiling and Disease Modelling in Engineered Vascular Smooth Muscle Cell Tissues. Matrix biology plus. 2022 16 : 100122. [Full Text] [PubMed] [DOI] |
| 3 | Barallobre-Barreiro J, Radovits T, Fava M, Mayr U, Lin WY, Ermolaeva E, Martínez-López D, Lindberg EL, Duregotti E, Daróczi L, Hasman M, Schmidt LE, Singh B, Lu R, Baig F, Siedlar AM, Cuello F, Catibog N, Theofilatos K, Shah AM, Crespo-Leiro MG, Doménech N, Hübner N, Merkely BP, Mayr M. The Extracellular Matrix in Heart Failure: The Role of Adamts5 In Proteoglycan Remodelling. Circulation. 2021 : . [Full Text] [PubMed] [DOI] |
| 4 | Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE. PCSK9 Activity Is Potentiated Through HDL Binding. Circulation Research. 2021 : . [Full Text] [PubMed] [DOI] |
| 5 | Sangiao-Alvarellos S, Theofilatos K, Barwari T, Gutmann C, Takov K, Singh B, Juiz-Valiña P, Varela-Rodríguez BM, Outeiriño-Blanco E, Duregotti E, Zampetaki A, Lunger L, Ebenbichler C, Tilg H, García-Brao MJ, Willeit P, Mena E, Kiechl S, Cordido F, Mayr M. Metabolic recovery after weight loss surgery is reflected in serum microRNAs. BMJ Open Diabetes Research and Care. 2020 8(2) : e001441. [Full Text] [PubMed] [DOI] |
| 6 | Negro S, Stazi M, Marchioretto M, Tebaldi T, Rodella U, Duregotti E, Gerke V, Quattrone A, Montecucco C, Rigoni M. Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells. RNA. 2018 24 : . [PubMed] [DOI] |
| 7 | Zanetti G, Duregotti E, Locatelli C, Giampreti A, Lonati D, Rossetto O, Pirazzini M . Variability in venom composition of European viper subspecies limits the cross-effectiveness of antivenoms. Scientific Report. 2018 8 : . [PubMed] [DOI] |
| 8 | Negro S, Lessi F, Duregotti E, Aretini P, La Ferla M, Franceschi S, Menicagli M, Bergamin E, Radice E, Thelen, M. CXCL12α/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals. EMBO Molecular Medicine. 2017 : . |
| 9 | Zanetti G, Sikorra S, Rummel A, Krez N, Duregotti E, Negro S, Henke T, Rossetto O, Binz T, Pirazzini M . Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission. PLoS Pathog. 2017 : . |
| 10 | Negro S, Bergamin E, Rodella U, Duregotti E, Scorzeto M, Jalink K, Montecucco C, Rigoni M . ATP released by injured neurons activates schwann cells. Frontiers Cellular Neuroscience. 2016 : . |
| 11 | Rodella U, Scorzeto M, Duregotti E, Negro S, Dickinson B, Chang C, Yuki N, Rigoni M, Montecucco C . An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells. Neurobiology Disorders. 2016 : . |
| 12 | Duregotti E, Negro S, Scorzeto M, Zornetta I, Dickinson B, Chang C, Montecucco C, Rigoni M . Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic schwann cells. Proc. Natl. Acad. Sci.. 2015 : . |
| 13 | Duregotti E, Zanetti G, Scorzeto M, Megighian A, Montecucco C, Pirazzini M, Rigoni M . Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction. Toxins. 2015 : . |
| 14 | Duregotti E, Tedesco E, Montecucco C, Rigoni M. Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins. Toxicon. 2013 : . |