Dr. Elisa Duregotti

Elisa Duregotti

Education


2006-2009 Bachelor Degree in Molecular Biology
Faculty of Mathematical, Physical and Natural Sciences, University of Padova, Padova, Italy
2009-2011 Master Degree in Medical Biology (110/110 cum laude)
Faculty of Mathematical, Physical and Natural Sciences, University of Padova, Padova, Italy
2012-2014 PhD in Biosciences and Biotechnologies (Cell Biology curriculum)
Prof. Cesare Montecucco Lab., Department of Biomediacal Sciences, University of Padova, Padova, Italy

Present Appointment


2017- Research Associate,
Cardiovascular Division, King’s College London, UK

Previous Appointment


2015-2017 Post-doctoral position
Prof. Cesare Montecucco, Department of Biomedical Sciences, University of Padova, Padova, Italy
2017-2018 Prof. Manuel Mayr Lab., Department of Cardiology, Cardiovascular Division, King’s College London
James Black Centre, 125 Coldharbour Lane, London,  United Kingdom, SE5 9NU

Publications


1 Negro S, Stazi M, Marchioretto M, Tebaldi T, Rodella U, Duregotti E, Gerke V, Quattrone A, Montecucco C, Rigoni M. Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells. RNA. 2018 24 : . [PubMed] [DOI]

2 Zanetti G, Duregotti E, Locatelli C, Giampreti A, Lonati D, Rossetto O, Pirazzini M . Variability in venom composition of European viper subspecies limits the cross-effectiveness of antivenoms. Scientific Report. 2018 8 : . [PubMed] [DOI]

3 Negro S, Lessi F, Duregotti E, Aretini P, La Ferla M, Franceschi S, Menicagli M, Bergamin E, Radice E, Thelen, M. CXCL12?/SDF-1 from perisynaptic Schwann cells promotes regeneration of injured motor axon terminals. EMBO Molecular Medicine. 2017 : .

4 Zanetti G, Sikorra S, Rummel A, Krez N, Duregotti E, Negro S, Henke T, Rossetto O, Binz T, Pirazzini M . Botulinum neurotoxin C mutants reveal different effects of syntaxin or SNAP-25 proteolysis on neuromuscular transmission. PLoS Pathog. 2017 : .

5 Negro S, Bergamin E, Rodella U, Duregotti E, Scorzeto M, Jalink K, Montecucco C, Rigoni M . ATP released by injured neurons activates schwann cells. Frontiers Cellular Neuroscience. 2016 : .

6 Rodella U, Scorzeto M, Duregotti E, Negro S, Dickinson B, Chang C, Yuki N, Rigoni M, Montecucco C . An animal model of Miller Fisher syndrome: Mitochondrial hydrogen peroxide is produced by the autoimmune attack of nerve terminals and activates Schwann cells. Neurobiology Disorders. 2016 : .

7 Duregotti E, Negro S, Scorzeto M, Zornetta I, Dickinson B, Chang C, Montecucco C, Rigoni M . Mitochondrial alarmins released by degenerating motor axon terminals activate perisynaptic schwann cells. Proc. Natl. Acad. Sci.. 2015 : .

8 Duregotti E, Zanetti G, Scorzeto M, Megighian A, Montecucco C, Pirazzini M, Rigoni M . Snake and spider toxins induce a rapid recovery of function of botulinum neurotoxin paralysed neuromuscular junction. Toxins. 2015 : .

9 Duregotti E, Tedesco E, Montecucco C, Rigoni M. Calpains participate in nerve terminal degeneration induced by spider and snake presynaptic neurotoxins. Toxicon. 2013 : .