2025-papers-test • Cardiovascular Proteomics

Publications 2025

Zoodsma, Martijn; Beuchel, Carl; Yasmeen, Summaira; Kohleick, Leonhard; Nepal, Aakash; Koprulu, Mine; Kronenberg, Florian; Mayr, Manuel; Williamson, Alice; Pietzner, Maik; Langenberg, Claudia. A genetic map of human metabolism across the allele frequency spectrum. Nature Genetics 2025

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Meena, Devendra; Huang, Jingxian; Smith, Alexander; Yarmolinsky, James; Wu, Siwei; Koskeridis, Fotios; Ko, Yi-Hsuan; Dib, Marie-Joe; Antonatos, Charalabos; Vasilopoulos, Yiannis; Yu, Xinzhu; Otto, Georg W; Gill, Dipender; Mayr, Manuel; Elliott, Paul; Dehghan, Abbas; Tzoulaki, Ioanna. Blood pressure, plasma proteins, and cardiovascular diseases: a network Mendelian randomization and observational study. European Heart Journal 2025

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van der Velpen, Vera; Häner, Jonas D; Kakizaki, Ryota; Bär, Sarah; Ueki, Yasushi; Siontis, George C M; Stortecky, Stefan; Biccirè, Flavio G; Ambühl, Maria; Kaiser, Christoph; Iglesias, Juan F; Mach, Francois; van Geuns, Robert J; Daemen, Joost; Engstrøm, Thomas; Ondracek, Anna S; Lang, Irene; Bourantas, Christos V; Matter, Christian M; Windecker, Stephan; Koskinas, Konstantinos C; Mayr, Manuel; Losdat, Sylvain; Räber, Lorenz; Haschke, Manuel; Spirk, David. Intake of high-intensity statin after acute myocardial infarction assessed by direct drug concentration measurement: association with LDL-C response and coronary plaque modifications in the PACMAN-AMI trial. European Journal of Preventive Cardiology 2025

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Cho, Hyun-Ju; Smith, Joy; Switzer, Christopher H; Louka, Eleni; Charles, Rebecca L; Prysyazhna, Oleksandra; Schroder, Ewald; Fernandez-Caggiano, Mariana; de Jesus, Daniel Simoes; Eminaga, Seda; Yin, Xiaoke; Yang, Xiaoping; Lynham, Steven; Mayr, Manuel; Morales, Valle; Bianchi, Katiuscia; Rajeeve, Vinothini; Cutillas, Pedro R; Mead, Adam J; Eaton, Philip. SFX-01 is therapeutic against myeloproliferative disorders caused by activating mutations in Shp2. EMBO Molecular Medicine 2025

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Smith, Alexander; Elliott, Paul; Mayr, Manuel; Dehghan, Abbas; Tzoulaki, Ioanna. Proteomic risk scores for predicting common diseases using linear and neural network models in the UK biobank. Scientific Reports 2025

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Yin, Xiaoke; Beele, Alicia; Theofilatos, Konstantinos; Baig, Ferheen; Hasman, Maria; Schmidt, Lukas E.; Boyle, Joseph J.; Turner, Adam W.; Miller, Clint L.; Pasterkamp, Gerard; Stojkovic, Stefan; Wojta, Johann; Joner, Michael; Mayr, Manuel. A Comparative Proteomics Study of Autopsy and Fresh-Frozen Coronary Artery Samples. Journal of Proteome Research 2025

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Gutmann, Clemens; Barwari, Temo; Schulte, Christian; Theofilatos, Konstantinos; Singh, Bhawana; Takov, Kaloyan; Suna, Gonca; Chan, Melissa V; Armstrong, Paul C; Cassel, Christian; Ueki, Yasushi; Häner, Jonas D; Santer, Peter; Willeit, Peter; Hengstenberg, Christian; Räber, Lorenz; Kiechl, Stefan; Willeit, Johann; Warner, Timothy D; Mayr, Manuel. Platelets and inflammation—insights from platelet non-coding RNA content and release in the Bruneck study and the PACMAN-AMI trial. Cardiovascular Research 2025

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Yin, Xiaoke; Mayr, Manuel. Cardiac regeneration beyond stem cells: harnessing sarcomere dynamics and endogenous repair mechanisms. Cardiovascular Research 2025

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Palm, Kaylin C A; Yin, Xiaoke; Baig, Ferheen; Theofilatos, Konstantinos; van der Laan, Sander W; de Borst, Gert J; de Kleijn, Dominique P V; Wojta, Johann; Stojkovic, Stefan; Mayr, Manuel; den Ruijter, Hester M; Pasterkamp, Gerard; Diez Benavente, Ernest; Mokry, Michal. Proteomic profiling reveals a higher presence of glycolytic enzymes in human atherosclerotic lesions with unfavourable histological characteristics. Cardiovascular Research 2025

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Singh, Bhawana; Tzoulaki, Ioanna; Mayr, Manuel. Precision medicine requires precision proteomics: discordance between proteomic and clinical assays in UK Biobank. Cardiovascular Research 2025

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Francois, Asvi Arora; Yin, Xiaoke; Oka, Shinichi; Sadoshima, Junichi; Mayr, Manuel; Eaton, Philip. On the utility of immobilized phenylarsine oxide in the study of redox sensitive cardiac proteins. Scientific Reports 2025

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Walther, Romy; Singh, Bhawana; Yin, Xiaoke; Mavberg, Philip; Mücke, Anna; Rodionov, Roman; Babir, Mahmoud; Mayr, Manuel; Bornstein, Stefan R.. Proteomic Profiling of Age-Related Proteins Following Extracorporeal Apheresis. Hormone and Metabolic Research 2025

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Fellows, Adam L.; Quigley, Kate; Leung, Venus; Ainscough, Alexander J.; Wilkins, Martin R.; Barnett, Harry; Miller, David; Mayr, Manuel; Wojciak‐Stothard, Beata. Engineered pulmonary artery tissues for measuring contractility, drug testing and disease modelling. British Journal of Pharmacology 2025

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Whitehead, Meredith; Faleeva, Maria; Oexner, Rafael; Cox, Susan; Schmidt, Lukas; Mayr, Manuel; Shanahan, Catherine M.. ECM Modifications Driven by Age and Metabolic Stress Directly Promote Vascular Smooth Muscle Cell Osteogenic Processes. Arteriosclerosis, Thrombosis, and Vascular Biology 2025

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Mayer-Suess, Lukas; Knoflach, Michael; Peball, Tamara; Mangesius, Stephanie; Steiger, Ruth; Pereverzyev, Sergiy; Lerchner, Hannes; Blache, Ludovic; Mayr, Manuel; Ratzinger, Gudrun; Kiechl, Stefan; Gizewski, Elke R.; Pechlaner, Raimund. Cervical Artery Tortuosity Is Associated With Dissection Occurrence and Late Recurrence: A Nested Case-Control Study. Stroke 2025

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Fellows, Adam L.; Chen, Chien-Nien; Xie, Chongyang; Iyer, Nayana; Schmidt, Lukas; Yin, Xiaoke; Yates, Luke A.; Mayr, Manuel; Cowburn, Andrew; Zhao, Lan; Wojciak-Stothard, Beata. ARF6 as a Novel Activator of HIF-2α in Pulmonary Arterial Hypertension. American Journal of Respiratory Cell and Molecular Biology 2025

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