Dr. Kaloyan Takov
Education
| 2011-2015 | BSc Biomedical Sciences with Honours Pharmacology (First Class) The University of Edinburgh |
| 2015-2019 | British Heart Foundation PhD in Cardiovascular Medicine University College London, UK |
Present Appointment
| 2023- | Research Associate, National Heart and Lung Institute Imperial College London London, UK |
Previous Appointment
| 2020-2023 | Research Associate Cardiovascular Division, King’s College London, London, UK |
Publications
| 1 | Burnap SA, Ortega-Prieto AM, Jimenez-Guardeño JM, Ali H, Takov K, Fish M, Shankar-Hari M, Giacca M, Malim MH, Mayr M. Cross-Linking Mass Spectrometry Uncovers Interactions Between High-Density Lipoproteins and the SARS-CoV-2 Spike Glycoprotein. Molecular & Cellular Proteomics. 2023 22(8) : 100600. [Full Text] [PubMed] [DOI] |
| 2 | Ragone I, Barallobre-Barreiro J, Takov K, Theofilatos K, Yin X, Schmidt LE, Domenech N, Crespo-Leiro MG, van der Voorn SM., Vink A, van Veen TA.B., Bödör C, Merkely B, Radovits T, Mayr M. SERCA2a Protein Levels Are Unaltered in Human Heart Failure. Circulation. 2023 148(7) : 613–616. [Full Text] [PubMed] [DOI] |
| 3 | Yin X, Takov K, Straube R, Voit-Bak K, Graessler J, Julius U, Tselmin S, Rodionov R, Barbir M, Walls M, Theofilatos K, Mayr M, Bornstein SR. Precision Medicine Approach for Cardiometabolic Risk Factors in Therapeutic Apheresis. Hormone and Metabolic Research. 2022 54(04) : 238-249. [PubMed] [DOI] |
| 4 | Davidson SM, Boulanger CM, Aikawa E, Badimon L, Barile L, Binder CJ, Brisson A, Buzas E, Emanueli C, Jansen F, Katsur M, Lacroix R, Lim SK, Mackman N, Mayr M, Menasché P, Nieuwland R, Sahoo S, Takov K, Thum T, Vader P, Wauben MHM, Witwer K, Sluijter JPG. Methods for the identification and characterization of extracellular vesicles in cardiovascular studies: from exosomes to microvesicles. Cardiovascular Research. 2022 : . [Full Text] [PubMed] [DOI] |
| 5 | Takov K, Teng IJ, Mayr M . Isolation of Circulating Extracellular Vesicles by High-Performance Size-Exclusion Chromatography. Extracellular Vesicles in Diagnosis and Therapy. 2022 : 31-40. [Full Text] [PubMed] [DOI] |
| 6 | Burnap SA, Sattler K, Pechlaner R, Duregotti E, Lu R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE. PCSK9 Activity Is Potentiated Through HDL Binding. Circulation Research. 2021 : . [Full Text] [PubMed] [DOI] |
| 7 | Burnap SA, Sattler K, Pechlaner R, Theofilatos K, Takov K, Heusch G, Tsimikas S, Fernández-Hernando C, Berry SE, Hall W, Notdurfter M. HDL compartmentalisation regulates PCSK9 activity. Atherosclerosis. 2021 331 : e39. [Full Text] [DOI] |
| 8 | Sangiao-Alvarellos S, Theofilatos K, Barwari T, Gutmann C, Takov K, Singh B, Juiz-Valiña P, Varela-Rodríguez BM, Outeiriño-Blanco E, Duregotti E, Zampetaki A, Lunger L, Ebenbichler C, Tilg H, García-Brao MJ, Willeit P, Mena E, Kiechl S, Cordido F, Mayr M. Metabolic recovery after weight loss surgery is reflected in serum microRNAs. BMJ Open Diabetes Research and Care. 2020 8(2) : e001441. [Full Text] [PubMed] [DOI] |
| 9 | Gutmann C, Takov K, Burnap S, Singh B, Theofilatos K, Reed E, Hasman M, Nabeebaccus A, Fish M, McPhail M, O'Gallagher K, Schmidt L, Cassel C, Rienks M, Yin X, Auzinger G, Napoli S, Mujib S, Trovato F, Sanderson B, Merrick B, Niazi U, Saqi M, Dimitrakopoulou K, Braun S, Kronstein-Wiedemann R, Doores K, Edgeworth J, Shah A, Bornstein S, Tonn T, Hayday A, Shankar-Hari M, Mayr M. SARS-CoV-2 RNAemia and proteomic biomarker trajectory inform prognostication in COVID-19 patients admitted to intensive care. . 2020 : . [Full Text] [DOI] |
| 10 | Takov K, Yellon D, Davidson S. Comparison of small extracellular vesicles isolated from plasma by ultracentrifugation or size-exclusion chromatography: yield, purity and functional potential. Journal of Extracellular Vesicles. 2019 8(1) : 1560809. |
| 11 | Davidson S, Riquelme J, Takov K, et al. Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non‐diabetic exosomes in vitro. Journal of Cellular and Molecular Medicine. 2018 22(1) : 141-151. |
| 12 | Takov K, Wu J, Denvir M, Smith L, Hadoke P . The role of androgen receptors in atherosclerosis. . Molecular and Cellular Endocrinology. 2018 465 : 82-91. |
| 13 | Nie S, Wang X, Sivakumaran P, Chong M, Liu X, Karnezis T, Bandara N, Takov K. (2018) . Biologically active constituents of the secretome of human W8B2+ cardiac stem cells. Scientific Reports. 2018 8 : 1579. |
| 14 | Takov K, Yellon D, Davidson S . Letter by Takov et al regarding article Fabrication of synthetic mesenchymal stem cells for the treatment of acute myocardial infarction in mice. Circulation Research. 2017 120(11) : e46-e47. |
| 15 | Takov K, Yellon D, Davidson S. Confounding factors in vesicle uptake studies using fluorescent lipophilic membrane dyes. Journal of Extracellular Vesicles. 2017 6(1) : 1388731. |
| 16 | Wu J, Hadoke P., Takov K, et al. Influence of androgen receptor in vascular cells on reperfusion following hindlimb ischaemia. PloS one. 2016 11(5) : e0154987. |
| 17 | Davidson S, Takov K, Yellon D. Exosomes and cardiovascular protection. Cardiovascular Drugs and Therapy. 2016 31(1) : 77-86. |