RESEARCH GROUP

Dr. Ursula Mayr

 

 

Education
1992-2000 Medical School, University of Innsbruck, Austria
1998-2000 MD thesis, Institute of Pathophysiology, Innsbruck, Austria

Foreign Electives
1997

Dept. of Medicine, Carbonear General Hospital,
Memorial University of New Foundland´s School of Medicine, Canada
1998

Dept. of Medicine, G. F. Jooste Hospital,
University of Cape Town, South Africa

Present Appointment
2006-

Research fellow
Cardiovascular Division, King's College London,
London, UK

Previous Appointment
2002-2004 Research fellow
Dept. of Cardiac and Vascular Sciences
St George's Hospital Medical School, London, UK

Awards & Prizes
1999 Scholarship of the "Hans und Blanca Moser Stiftung"

 

 

Publications

 

1 Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, Prokopi M, Mayr A, Weger S, Oberhollenzer F, Bonora E, Shah A, Willeit J, Mayr M. Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes. Circ Res. 2010; Epub ahead : . [Full Text] [PubMed] [DOI]
2 Simper D, Mayr U, Urbich C, Zampetaki A, Prokopi M, Didangelos A, Saje A, Mueller M, Benbow U, Newby A, Apweiler R, Rahman S, Dimmeler S, Xu Q, Mayr M. Comparative Proteomics Profiling Reveals Role of Smooth Muscle Progenitors in Extracellular Matrix Production. Arterioscler Thromb Vasc Biol. 2010; 30 : 1325-1332. [Full Text] [PubMed] [DOI]
3 Yin X, Cuello F, Mayr U, Hao Z, Hornshaw M, Ehler E, Avkiran M, Mayr M. Proteomic analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution. Mol Cell Proteomics. 2010; 9 : 497-509. [Full Text] [PubMed] [DOI]
4 Mayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM. Proteomics, Metabolomics, and Immunomics on Microparticles Derived from Human Atherosclerotic Plaques. Circ Cardiovasc Genet. 2009; 2 : 379-388. [Full Text] [PubMed] [DOI]
5 Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood. 2009; 114 : 723. [Full Text] [PubMed] [DOI]
6 Pula G, Mayr U, Evans C, Prokopi M, Vara DS, Yin X, Astroulakis Z, Xiao Q, Hill J, Xu Q, Mayr M. Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circ Res. 2009; 104 : 32-40. [Full Text] [PubMed] [DOI]
7 Mayr M, Zampetaki A, Sidibe A, Mayr U, Yin X, De Souza AI, Chung YL, Madhu B, Quax PH, Hu Y, Griffiths JR, Xu Q. Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived From the Arterial Media and Adventitial Progenitors of Apolipoprotein E-Deficient Mice. Circ Res. 2008; 102 : 1046-1056. [Full Text] [PubMed] [DOI]
8 Mayr M, Yusuf S, Weir G, Chung Y-L, Mayr U, Yin X, Ladroue C, Madhu B, Roberts N, De Souza A, Fredericks S, Stubbs M, Griffiths JR, Jahangiri M, Xu Q, Camm JA. Combined metabolomic and proteomic analysis of human atrial fibrillation. J Am Coll Cardiol. 2007; 51 : 585-594. [Full Text] [PubMed] [DOI]
9 Mayr U, Zou Y, Zhang Z, Dietrich H, Hu Y, Xu Q. Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair. Circulation Research. 2006; 98 : 412-420. [Full Text] [PubMed] [DOI]
10 Mayr M, Chung YL, Mayr U, Yin X, Ly L, Troy H, Fredericks S, Hu Y, Griffiths JR, Xu Q. Proteomic and Metabolomic Analyses of Atherosclerotic Vessels From Apolipoprotein E-Deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism. Arterioscler. Thromb. Vasc. Biol. 2005; 25 : 2135-2142. [Full Text] [PubMed] [DOI]
11 Yin X, Mayr M, Xiao Q, Mayr U, Tarelli E, Wait R, Wang W, Xu Q. Proteomic dataset of Sca-1+ progenitor cells. Proteomics. 2005; 5 : 4533-4545. [Full Text] [PubMed] [DOI]
12 Mayr U, Mayr M, Yin X, Begum S, Tarelli E, Wait R, Xu Q. Proteomic dataset of mouse aortic smooth muscle cells. Proteomics. 2005; 5 : 4546-4557. [Full Text] [PubMed] [DOI]
13 Tosney E, Mayr U, Zou Y, Thompson DW, Hu Y, and Xu Q. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. Circ Res. 2004; 94 : 1466-1473. [PubMed]
14 Mayr M, Mayr U, Chung Y-L, Yin X, Griffiths JR, Xu Q. Vascular proteomics: linking proteomic and metabolomic changes. Proteomics. 2004; 4 : 3751-3761. [Full Text] [PubMed] [DOI]
15 Mayr M, Chung YL, Mayr U, McGregor E, Troy H, Baier G, Leitges M, Dunn MJ, Griffiths JR, Xu Q. Loss of PKC-delta alters cardiac metabolism. Am J Physiol Heart Circ Physiol. 2004; 287 : H937-H945. [Full Text] [PubMed] [DOI]
16 Mayr M, Metzler B, Chung YL, McGregor E, Mayr U, Troy H, Hu Y, Leitges M, Pachinger O, Griffiths JR Dunn MJ, Xu Q. Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice. Am J Physiol Heart Circ Physiol. 2004; 287 : H946-H956. [Full Text] [PubMed] [DOI]
17 Mayr M, Siow R, Chung YL, Mayr U, Griffiths JR, Xu Q. Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta. Circ Res. 2004; 94 : e87-96. [Full Text] [PubMed] [DOI]
18 Mayr U, Mayr M, Li C, Wernig F, Dietrich H, Hu Y, and Xu Q. Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice. Circ Res. 2002; 90 : 197-204. [Full Text] [PubMed]
19 Leitges M, Mayr M, Braun U, Mayr U, Li C, Pfister G, Ghaffari-Tabrizi N, Baier G, Hu Y, and Xu Q. Exacerbated vein graft arteriosclerosis in PKCdelta-null mice. J Clin Invest. 2001; 108 : 1505-1512. [Full Text] [PubMed]
20 Dietrich H, Hu Y, Zou Y, Huemer U, Metzler B, Li C, Mayr M, and Xu Q. Rapid development of vein graft atheroma in apoE-deficient mice. Am J Pathol. 2000; 157 : 659-669. [Full Text] [PubMed]
21 Mayr M, Li C, Zou Y, Huemer U, Hu Y, and Xu Q. Biomechanical stress-induced apoptosis in vein grafts involves p38 mitogen-activated protein kinases. FASEB J. 2000; 14 : 261-270. [Full Text] [PubMed]