RESEARCH GROUP

Dr. Anna Zampetaki

 

 

Education
1994 Degree in Biology,
Aristotle University of Thessaloniki, GREECE
1996 PhD in Genetics,
Department of Genetics, Development and Molecular Biology,
School of Biology, Aristotle University of Thessaloniki, GREECE

Present Appointment
2006-

Postdoctoral Research Fellow
Department of Cardiology,

King's College London School of Medicine, London, U.K.

Previous Appointment
2000-2003 Postdoctoral Research Fellow
Children’s Hospital, Department of Newborn Medicine,
Harvard Medical School, Boston, USA.
2003-2006 Postdoctoral Research Fellow
Department of Cardiac and Vascular Sciences,
St. George’s Hospital Medical School, London, U.K.

 

 

Publications

 

1 Zampetaki A, Willeit P, Drozdov I, Kiechl S, Mayr M. Profiling of circulating microRNAs: from single biomarkers to re-wired networks.. Cardiovasc Res.. 2011; Epub ahead : . [Full Text] [PubMed] [DOI]
2 Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, Prokopi M, Mayr A, Weger S, Oberhollenzer F, Bonora E, Shah A, Willeit J, Mayr M. Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes. Circ Res. 2010; 107 : 810-817. [Full Text] [PubMed] [DOI]
3 Simper D, Mayr U, Urbich C, Zampetaki A, Prokopi M, Didangelos A, Saje A, Mueller M, Benbow U, Newby A, Apweiler R, Rahman S, Dimmeler S, Xu Q, Mayr M. Comparative Proteomics Profiling Reveals Role of Smooth Muscle Progenitors in Extracellular Matrix Production. Arterioscler Thromb Vasc Biol. 2010; 30 : 1325-1332. [Full Text] [PubMed] [DOI]
4 Margariti A, Zampetaki A, Xiao Q, Zhou B, Karamariti E, Martin D, Yin X, Mayr M, Li H, Zhang Z, De Falco E, Hu Y, Cockerill G, Xu Q, Zeng L. Histone Deacetylase 7 Controls Endothelial Cell Growth Through Modulation of beta-Catenin. Circ Res. 2010; 106 : 1202-1211. [Full Text] [PubMed] [DOI]
5 Zampetaki A, Zeng L, Margariti A, Xiao Q, Li H, Zhang Z, Pepe AE, Wang G, Habi O, deFalco E, Cockerill G, Mason JC, Hu Y, Xu Q. Histone deacetylase 3 is critical in endothelial survival and atherosclerosis development in response to disturbed flow. Circulation. 2010; 121 : 132-142. [PubMed] [DOI]
6 Zampetaki A, Xu Q. Vascular remodeling in diabetes: don't leave without your STAT5. Arterioscler Thromb Vasc Biol. 2009; 29 : 10-11.
7 Margariti A, Xiao Q, Zampetaki A, Zhang Z, Li H, Hu Y, Zeng L, Xu Q. HDAC7 Splicing Induces Smooth Muscle Cell Differentiation from Embryonic Stem Cells through Modulation of MEF2C. J Cell Sci. 2009; 122 : 460-470.
8 Zeng L, Zampetaki A, Margariti A, Li H, Zhang Z, Pepe AE, Alam S, Martin D, Xiao Q, Wang W, Jin Z, Cockerill G, Mori K, Hu Y, Xu Q. Sustained Activation of XBP1 Splicing Leads to Endothelial Cell Apoptosis and Atherosclerosis Development. PNAS. 2009; 106 : 8326-8331.
9 Zampetaki A, Kirton JP, Xu Q. Vascular repair by endothelial progenitor cells. Cardiovasc Res. 2008; 78 : 413-421.
10 Mayr M, Sidibe A, Zampetaki A. The paradox of hypoxic and oxidative stress in atherosclerosis. J Am Coll Cardiol. 2008; 51 : 1266-1267.
11 Mayr M, Zampetaki A, Sidibe A, Mayr U, Yin X, De Souza AI, Chung YL, Madhu B, Quax PH, Hu Y, Griffiths JR, Xu Q. Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived From the Arterial Media and Adventitial Progenitors of Apolipoprotein E-Deficient Mice. Circ Res. 2008; 102 : 1046-1056. [Full Text] [PubMed] [DOI]
12 Zampetaki A, Zeng L, Xiao Q, Margariti A, Hu Y, Xu Q. Lacking cytokine production in ES cells and ES-cell-derived vascular cells stimulated by TNF-alpha is rescued by HDAC inhibitor trichostatin A. Am J Physiol Cell Physiol. 2007; 293 : C1226-C1238.
13 Sidibe A, Yin X, Tarelli E, Xiao Q, Zampetaki A, Xu Q, Mayr M. Integrated Membrane Protein Analysis of Mature and Embryonic Stem Cell-derived Smooth Muscle Cells using a Novel Combination of Cy-dye/Biotin Labelling. Mol Cell Proteomics. 2007; 6 : 1788-1797. [Full Text] [PubMed] [DOI]
14 Zampetaki A, Xiao Q, Zeng L, Hu Y, Xu Q. TLR4 expression in mouse embryonic stem cells and in stem cell-derived vascular cells is regulated by epigenetic modifications. Biochem Biophys Res Commun. 2006; 347 : 89-99.
15 Zeng L, Xiao Q, Margariti A, Zhang Z, Zampetaki A, Patel S, Capogrossi MC, Hu Y, Xu Q. HDAC3 is crucial in shear- and VEGF-induced stem cell differentiation toward endothelial cells. J Cell Biol. 2006; 174 : 1059-1069.
16 Zampetaki A, Zhang Z, Hu Y, Xu Q. Biomechanical stress induces IL-6 expression in smooth muscle cells via Ras/Rac1-p38 MAPK-NF-kappaB signaling pathways. Am J Physiol Heart Circ Physiol. 2005; 288 : H2946-2954.
17 Zampetaki A, Mitsialis SA, Pfeilschifter J, Kourembanas S. Hypoxia induces macrophage inflammatory protein-2 (MIP-2) gene expression in murine macrophages via NF-kappaB: the prominent role of p42/p44 and PI3 kinase pathways. FASEB J. 2004; 18 : 1090-1092.
18 Zampetaki A, Minamino T, Mitsialis SA, Kourembanas S. Effect of heme oxygenase-1 overexpression in two models of lung inflammation. Exp Biol Med. 2003; 228 : 442-446.