Dr. Ursula Mayr

Dr. Ursula Mayr

Education


1992-2000 Medical School, University of Innsbruck, Austria
1998-2000 MD thesis, Institute of Pathophysiology, Innsbruck, Austria

 

Foreign Electives


1997 Dept. of Medicine, Carbonear General Hospital,
Memorial University of New Foundland´s School of Medicine, Canada
1998 Dept. of Medicine, G. F. Jooste Hospital,
University of Cape Town, South Africa

 

Present Appointment


2006- Research fellow
Cardiovascular Division, King’s College London,
London, UK

 

Previous Appointment


2002-2004 Research fellow
Dept. of Cardiac and Vascular Sciences
St George’s Hospital Medical School, London, UK

 

Awards & Prizes

Awards & Prizes


1999 Scholarship of the “Hans und Blanca Moser Stiftung”

 

Publications


1 Barwari T, Eminaga S, Mayr U, Lu R, Armstrong PC, Chan MV, Sahraei M, Fernández-Fuertes M, Moreau T, Barallobre-Barreiro J, Lynch M, Yin X, Schulte C, Baig F, Pechlaner R, Langley SR, Zampetaki A, Santer P, Weger M, Plasenzotti R, Schosserer M, Grillari J, Kiechl S, Willeit J, Shah AM, Ghevaert C, Warner TD, Fernández-Hernando C, Suárez Y, Mayr M. Inhibition of profibrotic microRNA-21 affects platelets and their releasate. JCI Insight. 2018 3 : e123335. [Full Text] [PubMed] [DOI]

2 Fava M, Barallobre-Barreiro J, Mayr U, Lu R, Didangelos A, Baig F, Lynch M, Catibog N, Joshi A, Barwari T, Yin X, Jahangiri M, Mayr M. Role of ADAMTS (A Disintegrin and Metalloproteinase With Thrombospondin Motifs)-5 in Aortic Dilatation and Extracellular Matrix Remodeling. Arterioscler Thromb Vasc Biol. 2018 38 : 1537-1548. [Full Text] [PubMed] [DOI]

3 Suna G, Wojakowski W, Lynch M, Barallobre-Barreiro J, Yin X, Mayr U, Baig F, Lu R, Fava M, Hayward R, Molenaar C, White SJ, Roleder T, Milewski K, Gasior P, Buszman PP, Buszman PE, Jahangiri M, Shanahan C, Hill JM, Mayr M. Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries. Circulation. 2018 137 : 166-183. [Full Text] [PubMed] [DOI]

4 Zampetaki A, Attia RQ, Mayr U, Gomes RS, Phinikaridou A, Yin X, Langley S, Willeit P, Lu R, Fanshawe B, Fava M, Barallobre-Barreiro J, Molenaar C, So PW, Abbas A, Jahangiri M, Waltham M, Botnar R, Smith A, Mayr M. Role of miR-195 in Aortic Aneurysmal Disease. Circ Res. 2014 115 : 857-866. [Full Text] [PubMed] [DOI]

5 Cuello F, Shankar-Hari M, Mayr U, Yin X, Marshall M, Suna G, Willeit P, Langley SR, Jayawardhana T, Zeller T, Terblanche M, Shah AM, Mayr M. Redox-state of pentraxin 3 as a novel biomarker for resolution of inflammation and survival in sepsis. Mol Cell Proteomics. 2014 13 : 2545-2557. [Full Text] [PubMed] [DOI]

6 Stegemann C, Pechlaner R, Willeit P, Langley S, Mangino M, Mayr U, Menni C, Moayyeri A, Santer P, Rungger G, Spector TD, Willeit J, Kiechl S, Mayr M. Lipidomics Profiling and Risk of Cardiovascular Disease in the Prospective Population-Based Bruneck Study. Circulation. 2014 129 : 1821-1831. [Full Text] [PubMed] [DOI]

7 Abonnenc M, Nabeebaccus AA, Mayr U, Barallobre-Barreiro J, Dong X, Cuello F, Sur S, Drozdov I, Langley S, Lu R, Stathopoulou K, Didangelos A, Yin X, Zimmermann WH, Shah AM, Zampetaki A, Mayr M. Extracellular Matrix Secretion by Cardiac Fibroblasts: Role of microRNA-29b and microRNA-30c. Circ Res. 2013 113 : 1138-1147. [Full Text] [PubMed] [DOI]

8 Yin X, Dwyer J, Langley S, Mayr U, Xing Q, Drozdov I, Nabeebaccus A, Shah A, Madhu B, Griffiths J, Edwards LM, Mayr M. Effects of Perhexiline-Induced Fuel Switch on the Cardiac Proteome and Metabolome. J Mol Cell Cardiol. 2013 55 : 27-30. [Full Text] [PubMed] [DOI]

9 Didangelos A, Mayr U, Monaco C, Mayr M. Novel role of ADAMTS-5 protein in proteoglycan turnover and lipoprotein retention in atherosclerosis. J Biol Chem. 2012 287 : 19341-19345. [Full Text] [PubMed] [DOI]

10 Zampetaki A, Kiechl S, Drozdov I, Willeit P, Mayr U, Prokopi M, Mayr A, Weger S, Oberhollenzer F, Bonora E, Shah A, Willeit J, Mayr M. Plasma MicroRNA Profiling Reveals Loss of Endothelial MiR-126 and Other MicroRNAs in Type 2 Diabetes. Circ Res. 2010 107 : 810-817. [Full Text] [PubMed] [DOI]

11 Simper D, Mayr U, Urbich C, Zampetaki A, Prokopi M, Didangelos A, Saje A, Mueller M, Benbow U, Newby A, Apweiler R, Rahman S, Dimmeler S, Xu Q, Mayr M. Comparative Proteomics Profiling Reveals Role of Smooth Muscle Progenitors in Extracellular Matrix Production. Arterioscler Thromb Vasc Biol. 2010 30 : 1325-1332. [Full Text] [PubMed] [DOI]

12 Yin X, Cuello F, Mayr U, Hao Z, Hornshaw M, Ehler E, Avkiran M, Mayr M. Proteomic analysis of the cardiac myofilament subproteome reveals dynamic alterations in phosphatase subunit distribution. Mol Cell Proteomics. 2010 9 : 497-509. [Full Text] [PubMed] [DOI]

13 Mayr M, Grainger D, Mayr U, Leroyer AS, Leseche G, Sidibe A, Herbin O, Yin X, Gomes A, Madhu B, Griffiths JR, Xu Q, Tedgui A, Boulanger CM. Proteomics, Metabolomics, and Immunomics on Microparticles Derived from Human Atherosclerotic Plaques. Circ Cardiovasc Genet. 2009 2 : 379-388. [Full Text] [PubMed] [DOI]

14 Prokopi M, Pula G, Mayr U, Devue C, Gallagher J, Xiao Q, Boulanger CM, Westwood N, Urbich C, Willeit J, Steiner M, Breuss J, Xu Q, Kiechl S, Mayr M. Proteomic analysis reveals presence of platelet microparticles in endothelial progenitor cell cultures. Blood. 2009 114 : 723. [Full Text] [PubMed] [DOI]

15 Pula G, Mayr U, Evans C, Prokopi M, Vara DS, Yin X, Astroulakis Z, Xiao Q, Hill J, Xu Q, Mayr M. Proteomics identifies thymidine phosphorylase as a key regulator of the angiogenic potential of colony-forming units and endothelial progenitor cell cultures. Circ Res. 2009 104 : 32-40. [Full Text] [PubMed] [DOI]

16 Mayr M, Zampetaki A, Sidibe A, Mayr U, Yin X, De Souza AI, Chung YL, Madhu B, Quax PH, Hu Y, Griffiths JR, Xu Q. Proteomic and Metabolomic Analysis of Smooth Muscle Cells Derived From the Arterial Media and Adventitial Progenitors of Apolipoprotein E-Deficient Mice. Circ Res. 2008 102 : 1046-1056. [Full Text] [PubMed] [DOI]

17 Mayr M, Yusuf S, Weir G, Chung Y-L, Mayr U, Yin X, Ladroue C, Madhu B, Roberts N, De Souza A, Fredericks S, Stubbs M, Griffiths JR, Jahangiri M, Xu Q, Camm JA. Combined metabolomic and proteomic analysis of human atrial fibrillation. J Am Coll Cardiol. 2008 51 : 585-594. [Full Text] [PubMed] [DOI]

18 Mayr U, Zou Y, Zhang Z, Dietrich H, Hu Y, Xu Q. Accelerated arteriosclerosis of vein grafts in inducible NO synthase(-/-) mice is related to decreased endothelial progenitor cell repair. Circ Res. 2006 98 : 412-420. [Full Text] [PubMed] [DOI]

19 Mayr U, Mayr M, Yin X, Begum S, Tarelli E, Wait R, Xu Q. Proteomic dataset of mouse aortic smooth muscle cells. Proteomics. 2005 5 : 4546-4557. [Full Text] [PubMed] [DOI]

20 Yin X, Mayr M, Xiao Q, Mayr U, Tarelli E, Wait R, Wang W, Xu Q. Proteomic dataset of Sca-1+ progenitor cells. Proteomics. 2005 5 : 4533-4545. [Full Text] [PubMed] [DOI]

21 Mayr M, Chung YL, Mayr U, Yin X, Ly L, Troy H, Fredericks S, Hu Y, Griffiths JR, Xu Q. Proteomic and Metabolomic Analyses of Atherosclerotic Vessels From Apolipoprotein E-Deficient Mice Reveal Alterations in Inflammation, Oxidative Stress, and Energy Metabolism. Arterioscler. Thromb. Vasc. Biol. 2005 25 : 2135-2142. [Full Text] [PubMed] [DOI]

22 Mayr M, Mayr U, Chung Y-L, Yin X, Griffiths JR, Xu Q. Vascular proteomics: linking proteomic and metabolomic changes. Proteomics. 2004 4 : 3751-3761. [Full Text] [PubMed] [DOI]

23 Mayr M, Metzler B, Chung YL, McGregor E, Mayr U, Troy H, Hu Y, Leitges M, Pachinger O, Griffiths JR Dunn MJ, Xu Q. Ischemic preconditioning exaggerates cardiac damage in PKC-delta null mice. Am J Physiol Heart Circ Physiol. 2004 287 : H946-H956. [Full Text] [PubMed] [DOI]

24 Mayr M, Chung YL, Mayr U, McGregor E, Troy H, Baier G, Leitges M, Dunn MJ, Griffiths JR, Xu Q. Loss of PKC-delta alters cardiac metabolism. Am J Physiol Heart Circ Physiol. 2004 287 : H937-H945. [Full Text] [PubMed] [DOI]

25 Mayr M, Siow R, Chung YL, Mayr U, Griffiths JR, Xu Q. Proteomic and metabolomic analysis of vascular smooth muscle cells: role of PKCdelta. Circ Res. 2004 94 : e87-96. [Full Text] [PubMed] [DOI]

26 Tosney E, Mayr U, Zou Y, Thompson DW, Hu Y, and Xu Q. Thrombosis and neointima formation in vein grafts are inhibited by locally applied aspirin through endothelial protection. Circ Res. 2004 94 : 1466-1473. [PubMed]

27 Mayr U, Mayr M, Li C, Wernig F, Dietrich H, Hu Y, and Xu Q. Loss of p53 accelerates neointimal lesions of vein bypass grafts in mice. Circ Res. 2002 90 : 197-204. [Full Text] [PubMed]

28 Leitges M, Mayr M, Braun U, Mayr U, Li C, Pfister G, Ghaffari-Tabrizi N, Baier G, Hu Y, and Xu Q. Exacerbated vein graft arteriosclerosis in PKCdelta-null mice. J Clin Invest. 2001 108 : 1505-1512. [Full Text] [PubMed]