Ms. Ferheen Baig

Ferheen Baig

Ferheen is a Research Assistant and Part time PhD student in the Cardiovascular Division at King’s College London where she works within Prof Manuel Mayr’s Proteomics group, providing support on all mass spectrometry related projects. Her role includes developing methods for untargeted and targeted nano-LC-MS/MS for the discovery and analysis of extracellular matrix proteins in samples from cardiovascular disease and related disorders.

As well as carrying out research for her PhD project, she is responsible for developing novel ‘fit for purpose’ targeted MRM methods for the quantification of extracellular matrix proteins, including their glycosylations, fragmentation and isoforms.

After receiving a BSc in Biomedical Science from King’s College and an MSc in Forensic Science from London South Bank University, Ferheen was employed by the pharmaceutical industry for 7 years where she worked mainly on small molecules as a bioanalyst for Drug Metabolism & Pharmacokinteic (DMPK) departments at GlaxoSmithKline and more recently at Novartis. Towards the end of her time at Novartis she began working on biomarker quantification including large molecules, prompting her interest in proteomics.

 

Education


2001-2004 BSc (Honours) Biomedical Science,
Kings College London, UK
2004-2005 MSc Forensic Science,
London South Bank University, UK

 

Present Appointment


2014- Research Assistant,
Cardiovascular Division, King’s College London, UK

 

Previous Appointment


2012-2014 Protein & Biomarker LCMS Scientist,
Metabolism & Pharmacokinetics,
NOVARTIS, Horsham, UK
2009-2012 Bioanalytical Scientist,
Metabolism & Pharmacokinetics,
NOVARTIS, Horsham, UK
2006-2009 Bioanalytical Associate ,
Drug Metabolism & Pharmacokinetics,
GLAXOSMITHKLINE, Ware, UK

 

Publications


1 Fava M, Barallobre-Barreiro J, Mayr U, Lu R, Didangelos A, Baig F, Lynch M, Catibog N, Joshi A, Barwari T, Yin X, Jahangiri M, Mayr M. Role of ADAMTS (A Disintegrin and Metalloproteinase With Thrombospondin Motifs)-5 in Aortic Dilatation and Extracellular Matrix Remodeling. Arterioscler Thromb Vasc Biol. 2018 Epub : ahead of print. [Full Text] [PubMed] [DOI]

2 Suna G, Wojakowski W, Lynch M, Barallobre-Barreiro J, Yin X, Mayr U, Baig F, Lu R, Fava M, Hayward R, Molenaar C, White SJ, Roleder T, Milewski K, Gasior P, Buszman PP, Buszman PE, Jahangiri M, Shanahan C, Hill JM, Mayr M. Extracellular Matrix Proteomics Reveals Interplay of Aggrecan and Aggrecanases in Vascular Remodeling of Stented Coronary Arteries. Circulation. 2018 137 : 166-183. [Full Text] [PubMed] [DOI]

3 Yin X, Baig F, Haudebourg E, Blankley RT, Gandhi T, Mller S, Reiter L, Hinterwirth H, Pechlaner R, Tsimikas S, Santer P, Willeit J, Kiechl S, Witztum JL, Sullivan A, Mayr M. Plasma Proteomics for Epidemiology: Increasing Throughput With Standard-Flow Rates. Circ Cardiovasc Genet. 2017 10 : e001808. [Full Text] [PubMed] [DOI]

4 Baig F, Mayr M. What are the prospects of apolipoprotein profiling for cardiovascular disease?. Expert Rev Mol Diagn. 2017 Epub : ahead of print. [Full Text] [PubMed] [DOI]

5 Barallobre-Barreiro J, Baig F, Fava M, Yin X, Mayr M. Glycoproteomics of the Extracellular Matrix: A Method for Intact Glycopeptide Analysis Using Mass Spectrometry. J Vis Exp. 2017 122 : . [Full Text] [PubMed] [DOI]

6 Pechlaner R, Tsimikas S, Yin X, Willeit P, Baig F, Santer P, Oberhollenzer F, Egger G, Witztum JL, Alexander VJ, Willeit J, Kiechl S, Mayr.. Very-Low-Density Lipoprotein-Associated Apolipoproteins Predict Cardiovascular Events and Are Lowered by Inhibition of APOC-III. J Am Coll Cardiol. 2017 69 : 789-800. [Full Text] [PubMed] [DOI]

7 Baig F, Joshi A, Mayr M. High Density Lipoproteins in High Resolution: Will Proteomics Solve the Paradox for Cardiovascular Risk?. Proteomics. 2017 17 : 3-4. [Full Text] [PubMed] [DOI]

8 Baig F, Pechlaner R, Mayr M. Caveats of Untargeted Metabolomics for Biomarker Discovery. J Am Coll Cardiol. 2016 68 : 1294-1296. [Full Text] [PubMed] [DOI]

9 Barallobre-Barreiro J, Oklu R, Lynch M, Fava M, Baig F, Yin X, Barwari T, Potier D, Albadawi H, Jahangiri M, Porter K, Watkins M, Misra S, Stoughton J, Mayr M. Extracellular Matrix Remodeling in Response to Venous Hypertension: Proteomics of Human Varicose Veins. Cardiovasc Res. 2016 110 : 419-430. [Full Text] [PubMed] [DOI]

10 Baig F, Mayr M. What can we learn from metabolomics?. Heart Metab. 2015 67 : 21-25. [Full Text]