Dr. Abhishek Joshi
Dr Joshi is a cardiology registrar, sub-specialising in cardiac imaging and interventions. He was recently awarded a BHF Clinical Research Training Fellowship, where he will investigate how individual differences in platelets change the risk of heart attacks, using the advanced proteomic techniques available at the James Black Centre. His PhD is supervised by Prof. Manuel Mayr and Prof. Anthony Mathur, as part of a join project between King’s College, London, and the Bart’s Heart Centre. His long term goal is to better predict, and so hopefully prevent, heart attacks.
Education
| 2000-2003 | BA, Philosophy, Psychology and Physiology, The Queen’s College, University of Oxford, Oxford, UK |
| 2004-2008 | Medicine (Fast Track), BMBCh, St. Hugh’s College, University of Oxford, Oxford, UK Elective at Mount Sinai School of Medicine (Paediatric Cardiology) |
| 2016- | PhD Student, Cardiovascular Division, King’s College London, London, UK |
Present Appointment
| 2015.10- | Cardiology Registrar (ST6) Sub-specialty training in Imaging and Intervention, Bart’s Heart Centre, London, UK |
Previous Appointment
| 2014-2015 | Advanced imaging training in cardiac MRI, cardiac CT, transoesophageal echocardiography, stress echocardiography, critical care cardiology. |
| 2013-2014 | Cardiology Registrar (ST4/ST5), London Chest Hospital/Bart’s Heart Centre, NE Thames Tertiary interventional cardiology referral centre Experience with cardiac CT, MRI, echocardiography, angiography and angioplasty, cardiomyopathy, advanced heart failure therapies, infective endocarditis. |
| 2013-2014 | Cardiology Registrar (ST4), St. Bartholomew’s Hospital, NE Thames Tertiary cardiac electrophysiology referral centre Experience with pacing and EP procedures |
| 2012-2013 | Cardiology Registrar (ST3), Whipps University Cross Hospital, NE Thames Extensive experience in general cardiology Emergency and acute medicine |
| 2010-2012 | Core Medical Trainee (CMT 1&2), South London Deanery Guy’s and St. Thomas’ NHS Trust, South London NHS Trust |
| 2008-2010 | Foundation Trainee (FY1&2), South Thames Foundation School Conquest Hospital, Hastings and Guy’s & St. Thomas’ Hospital |
| 2003-2004 | Clinical Support Worker, Countess of Chester Hospital Healthcare assistant with extended role |
Publications
| 1 | Armstrong PC, Allan HE, Kirkby NS, Gutmann C, Joshi A, Crescente M, Mitchell JA, Mayr M, Warner TD. Temporal in vivo platelet labelling in mice reveals age-dependent receptor expression and conservation of specific mRNAs. Blood Advances. 2022 : . [Full Text] [PubMed] [DOI] |
| 2 | Joshi A, Schmidt LE, Burnap SA, Lu R, Chan MV, Armstrong PC, Baig F, Gutmann C, Willeit P, Santer P, Barwari T, Theofilatos K, Kiechl S, Willeit J, Warner T, Mathur A, Mayr M. Neutrophil-Derived Protein S100A8/A9 Alters the Platelet Proteome in Acute Myocardial Infarction and Is Associated With Changes in Platelet Reactivity. Arteriosclerosis, thrombosis, and vascular biology. 2021 : ATVBAHA-121. [Full Text] [PubMed] [DOI] |
| 3 | Schulte C, Barwari T, Joshi A, Zeller T, Mayr M.. Noncoding RNAs versus protein biomarkers in cardiovascular disease. Trends in Molecular Medicine. 2020 26(6) : 583-596. [Full Text] [PubMed] [DOI] |
| 4 | Gutmann C, Joshi A, Mayr M. Platelet "-omics" in health and cardiovascular disease. Atherosclerosis. 2020 : . [Full Text] [PubMed] [DOI] |
| 5 | Gutmann C, Joshi A, Zampetaki A, Mayr M. The Landscape of Coding and Non-coding RNAs in Platelets. Antioxidants & Redox Signaling. 2020 : . [Full Text] [DOI] |
| 6 | Burnap SA, Joshi A, Tsimikas S, Fernández-Hernando C, Kiechl S, Berry SE, Hall W, Levkau B, Mayr M. High-Density Lipoproteins Are the Main Carriers of PCSK9 in the Circulation. J Am Coll Cardiol. 2020 75(12) : 1495-1497. [Full Text] [PubMed] [DOI] |
| 7 | Braza-Boïls A, Barwari T, Gutmann C, Thomas MR, Judge HM, Joshi A, Pechlaner R, Shankar-Hari M, Ajjan RA, Sabroe I, Storey RF, Mayr M. Circulating MicroRNA Levels Indicate Platelet and Leukocyte Activation in Endotoxemia Despite Platelet P2Y12 Inhibition. Int J Mol Sci. 2020 21(8) : 2897. [Full Text] [PubMed] [DOI] |
| 8 | Schulte C, Joshi A, Mayr M.. Response by Schulte et al to Letter Regarding Article, Comparative Analysis of Circulating Noncoding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury. Circ Res.. 2019 125(4) : e22-e23. [Full Text] [PubMed] [DOI] |
| 9 | Schulte C, Barwari T, Joshi A, Theofilatos K, Zampetaki A, Barallobre-Barreiro J, Singh B, Sorensen N, Neumann JT, Zeller T, Westermann D.. Comparative Analysis of Circulating Non-Coding RNAs Versus Protein Biomarkers in the Detection of Myocardial Injury. Circulation research. 2019 Epub : . [Full Text] [PubMed] [DOI] |
| 10 | Joshi A, Mayr M. In Aptamers They Trust: The Caveats of the SOMAscan Biomarker Discovery Platform from SomaLogic. Circulation. 2018 138 : 2482-2485. [Full Text] [PubMed] [DOI] |
| 11 | Rienks M, Joshi A, Mayr M. MicroRNA-24 and the Diabetic Heart. JACC: Basic to Translational Science. 2018 3 : 363-365. [Full Text] [PubMed] [DOI] |
| 12 | Fava M, Barallobre-Barreiro J, Mayr U, Lu R, Didangelos A, Baig F, Lynch M, Catibog N, Joshi A, Barwari T, Yin X, Jahangiri M, Mayr M. Role of ADAMTS (A Disintegrin and Metalloproteinase With Thrombospondin Motifs)-5 in Aortic Dilatation and Extracellular Matrix Remodeling. Arterioscler Thromb Vasc Biol. 2018 38 : 1537-1548. [Full Text] [PubMed] [DOI] |
| 13 | Barwari T, Joshi A, Mayr M. Reply: The Complex miRNAs-p53 Signaling Network in Cardiovascular Disease. J Am Coll Cardiol. 2017 16 : 2100. [Full Text] [PubMed] [DOI] |
| 14 | Sunderland N, Skroblin P, Barwari T, Huntley RP, Lu R, Joshi A, Lovering RC, Mayr M. MicroRNA Biomarkers and Platelet Reactivity: The Clot Thickens. Circ Res. 2017 20 : 418-435. [Full Text] [PubMed] [DOI] |
| 15 | Baig F, Joshi A, Mayr M. High Density Lipoproteins in High Resolution: Will Proteomics Solve the Paradox for Cardiovascular Risk?. Proteomics. 2017 17 : 3-4. [Full Text] [PubMed] [DOI] |
| 16 | Barwari T, Joshi A, Mayr M . MicroRNAs in Cardiovascular Disease. J Am Coll Cardiol. 2016 13 : 2577-2584. [Full Text] [PubMed] [DOI] |